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Article

The L10P polymorphism and serum levels of transforming growth factor β1 in human breast cancer.

International journal of molecular sciences - 24 Jul 2013

Taubenschuß Eva, Marton Erika, Mogg Maurice, Frech Barbara, Ehart Lisa, Muin Dana, Schreiber Martin

Abstract excerpt

The L10P single nucleotide polymorphism (SNP) is located in the signal sequence of the transforming growth factor β1 (TGFβ1) gene. The proline-encoding (Pro-) allele of this SNP has been associated with an increased breast cancer risk, which has been attributed to the elevated secretion of this TGFβ1 variant observed in vitro and in male subjects. Here we investigated the association of the L10P SNP with serum...

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Source

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Identifiers

PMID: 23887657
DOI: 10.3390/ijms140815376
PMCID: PMC3759865

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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