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Article

Transforming growth factorβ1 L10P variant plays an active role on the breast cancer susceptibility in Caucasian: evidence from 10,392 cases and 11,697 controls.

Breast cancer research and treatment - 1 Nov 2010

Ma Xiangyu, Chen Chunhai, Xiong Hongyan, Li Yafei

Abstract excerpt

In view of the essential role of transforming growth factorβ1 (TGFB1) on both inhibiting the development of early benign breast tumors as well as promoting tumor invasion, the association of TGFB1 L10P polymorphism and breast cancer risk has been widely reported, but results of previous studies were somewhat contradictory and underpowered. To overcome the limitations of individual study and to understand the real...

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Source

Identifiers

PMID: 20349130
DOI: 10.1007/s10549-010-0843-x

Genes

TGFB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Transforming growth factorβ1 L10P variant plays an active role on the breast cancer susceptibility in Caucasian: evidence from 10,392 cases and 11,697 controls.PMID 20349130Read ↗

TGFB1 L10P polymorphism is associated with breast cancer susceptibility: evidence from a meta-analysis involving 47,817 subjects.Semantic proximity Read ↗

Transforming growth factor-beta1 polymorphisms and breast cancer risk: a meta-analysis based on 27 case-control studies.Semantic proximity Read ↗

Association of TGFB1 -509 C>T polymorphism with breast cancer: evidence from a meta-analysis involving 23,579 subjects.Semantic proximity Read ↗

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Association of a TGF-β1 gene -509 C/T polymorphism with breast cancer risk: a meta-analysis.Semantic proximity Read ↗

No association of TGFB1 L10P genotypes and breast cancer risk in BRCA1 and BRCA2 mutation carriers: a multi-center cohort study.Semantic proximity Read ↗

Association of TGF-β1 -509C/T polymorphisms with breast cancer risk: evidence from an updated meta-analysis.Semantic proximity Read ↗

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Transforming growth factor beta1 (TGFβ1) polymorphisms and breast cancer risk.Semantic proximity Read ↗

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Effects of interleukin-10 polymorphisms (rs1800896, rs1800871, and rs1800872) on breast cancer risk: evidence from an updated meta-analysis.Semantic proximity Read ↗

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