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TGFB1 L10P polymorphism is associated with breast cancer susceptibility: evidence from a meta-analysis involving 47,817 subjects.

Breast cancer research and treatment - 1 Sept 2010

Qiu Li-Xin, Yao Lei, Mao Chen, Chen Bo, Zhan Ping, Xue Kai, Zhang Jian, Yuan Hui, Hu Xi-Chun

Abstract excerpt

Published data on the association between TGFB1 L10P polymorphism and breast cancer risk are inconclusive. In order to derive a more precise estimation of the relationship, a meta-analysis was performed. Crude ORs with 95% CIs were used to assess the strength of association between them. A total of 30 studies including 20,401 cases and 27,416 controls were involved in this meta-analysis. Overall, significantly...

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Identifiers

PMID: 20143152
DOI: 10.1007/s10549-010-0781-7

Genes

TGFB1

Variants

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