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Article

TGFβ1 Leu10Pro polymorphism contributes to the development of prostate cancer: evidence from a meta-analysis.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jan 2014

Cai Qiliang, Tang Yang, Zhang Minghao, Shang Zhiqun, Li Gang, Tian Jing, Jiang Ning, Quan Changyi, Niu Yuanjie

Abstract excerpt

Transforming growth factor-β1 (TGFβ1) plays a significant role in regulating cellular proliferation and apoptosis. A large number of studies related to the association between TGFβ1 Leu10Pro polymorphism and prostate cancer (PC) risk, but get conflicting results. We performed a meta-analysis based on six studies, assessing the strength of the association using odds ratios (OR) with 95% confidence intervals (CI)....

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PMID: 23975370
DOI: 10.1007/s13277-013-1092-5

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