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Article

Role of poly(ADP-ribose) polymerases in male reproduction

1 Apr 2013

Abstract excerpt

Poly(ADP-ribose) polymerases (PARPs) are a family of enzymes involved in a wide variety of biological processes, including DNA repair and maintenance of genomic stability following genotoxic stress, and regulates the expression of various proteins at the transcriptional level as well as replication and differentiation. However, excessive activation of PARP has been shown to contribute to the pathogenesis of...

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PMID: 23885303
DOI: 10.4161/spmg.24194

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