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Article

Replication proteins and human disease.

Cold Spring Harbor perspectives in biology - 1 Jan 2014

Jackson Andrew P, Laskey Ronald A, Coleman Nicholas

Abstract excerpt

In this article, we discuss the significance of DNA replication proteins in human disease. There is a broad range of mutations in genes encoding replication proteins, which result in several distinct clinical disorders that share common themes. One group of replication proteins, the MCMs, has emerged as effective biomarkers for early detection of a range of common cancers. They offer practical and theoretical...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23881941
DOI: 10.1101/cshperspect.a013060
PMCID: PMC3941220

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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