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Pan-Cancer Multi-Omics Analysis of Minichromosome Maintenance Proteins (MCMs) Expression in Human Cancers

27 Sept 2023

Abstract excerpt

Background: Epigenetic modifications, such as transcription, DNA repair, and replication significantly influence tumour development. Aberrant gene expression and modifications can have a crucial impact on the initiation and progression of tumours. The minichromosome maintenance (MCM) protein family, which is responsible for DNA synthesis, plays a crucial role in tumorigenesis and chemotherapy resistance by...

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Cancer-related Molecular Pathways
DNA Repair Mechanisms
Genetic factors in colorectal cancer

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37796706
DOI: 10.31083/j.fbl2809230

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