Aberrant DNA replication in cancer.

doi:10.1016/j.mrfmmm.2012.07.003

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Article

Aberrant DNA replication in cancer.

Mutation research - 1 Jan 2000

Suzuki Motoshi, Takahashi Takashi

Abstract excerpt

Genomic instability plays an important role in cancer susceptibility, though the mechanics of its development remain unclear. An often-stated hypothesis is that error-prone phenotypes in DNA replication or aberrations in translesion DNA synthesis lead to genomic instability and cancer. Mutations in core DNA replication proteins have been identified in human cancer, although DNA replication is essential for cell...

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Identifiers

PMID: 22968031
DOI: 10.1016/j.mrfmmm.2012.07.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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