Article
[Meta-analysis of association between E-cadherin promoter methylation and lung cancer risk].
Zhongguo fei ai za zhi = Chinese journal of lung cancer - 1 Jul 2013
Zeng Yuanyuan, Liu Rengyun, Zhang Hongtao
Abstract excerpt
BACKGROUND AND OBJECTIVE: As a member of the cadherin superfamily, E-cadherin plays a critical role in the maintenance of cell polarity and integrity. And E-cadherin was reported to be down-regulated and closely related to tumor initiation, invasion and metastasis. There have been a number of studies investigating the methylation of E-cadherin promoter in relation to various cancers. However, the association...
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