Article
High expression of E-cadherin in pleural effusion cells predicts better prognosis in lung adenocarcinoma patients.
International journal of clinical and experimental pathology - 1 Jan 2015
Zhao Chao, Li Xuefei, Su Chunxia, Li Jiayu, Cheng Ningning, Ren Shengxiang, Chen Xiaoxia, Zhou Caicun
Abstract excerpt
BACKGROUND: Epithelial-mesenchymal transition (EMT) is of great importance in tumor metastasis. Our previous study demonstrates that epithelial phenotype is related to epidermal growth factor receptor (EGFR) mutation and the sensitivity of EGFR tyrosine kinase inhibitors (TKIs) in advanced non-small cell lung cancer (NSCLC) patients. However, the role of EMT phenotype in malignant pleural effusions in predicting...
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