Genetic polymorphism in the 3'-untranslated region of the E-cadherin gene is associated with risk of different cancers.

doi:10.1002/mc.20765

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Article

Genetic polymorphism in the 3'-untranslated region of the E-cadherin gene is associated with risk of different cancers.

Molecular carcinogenesis - 1 Nov 2011

Li Yan, Tang Yuanjia, Zhou Rongmiao, Sun Donglan, Duan Yanan, Wang Na, Chen Zhifeng, Shen Nan

Abstract excerpt

The genetic polymorphisms in E-cadherin gene (CDH1) may affect invasive/metastatic disease development by altering gene transcriptional activity. In this paper, we investigated the effect of 3'-UTR +54C/T polymorphism (rs1801026) in CDH1 gene on the risk and progression of several common cancers. Multiple completely independent case-control analyses of 1081 cancer patients with esophageal squamous cell carcinoma...

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Identifiers

PMID: 21432908
DOI: 10.1002/mc.20765

Genes

CDH1
GCA

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