Article
Quantitative assessment of the diagnostic role of FHIT promoter methylation in non-small cell lung cancer.
Oncotarget - 24 Jan 2017
Geng Xin, Pu Weilin, Tan Yulong, Lu Zhouyi, Wang An, Tan Lixing, Chen Sidi, Guo Shicheng, Wang Jiucun, Chen Xiaofeng
Abstract excerpt
Aberrant methylation of CpG islands acquired in promoter regions plays an important role in carcinogenesis. Accumulated evidence demonstrates FHIT gene promoter hyper-methylation is involved in non-small cell lung cancer (NSCLC). To test the diagnostic ability of FHIT methylation status on NSCLC, thirteen studies, including 2,119 samples were included in our meta-analysis. Simultaneously, four independent DNA...
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