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Article

Correlation of E-cadherin gene polymorphisms and epidermal growth factor receptor mutation in lung adenocarcinoma.

International journal of medical sciences - 1 Jan 2018

Huang Chun-Yao, Hsieh Ming-Ju, Liu Tu-Chen, Chiang Whei-Ling, Liu Ming-Che, Yang Shun-Fa, Tsao Thomas Chang-Yao

Abstract excerpt

Epithelial-mesenchymal transition (EMT) was recently discovered related to the efficacy of epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) in NSCLC patients and cell lines. In this study, we aimed to explore the association among the E-cadherin gene (CDH1) genetic variants, TK-domain mutations of EGFR, and clinicopathologic characteristics in patients with lung adenocarcinoma. A total of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 30008585
DOI: 10.7150/ijms.24051
PMCID: PMC6036082

Genes

CDH1
EGFR

Variants

rs16260

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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