Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Promoter hypermethylation of Wnt inhibitory factor-1 in patients with lung cancer: A systematic meta-analysis.

Medicine - 1 Dec 2016

Zheng Yu, Li Xia, Jiang Yiming, Xu Yufen, Song Binbin, Zhou Qiang, Liang Xiaodong, Yang Xinmei

Abstract excerpt

BACKGROUND: Promoter hypermethylation of Wnt inhibitory factor-1 (WIF-1)-a tumor suppressor gene-has been detected in several types of human tumors. However, the association between WIF-1 promoter hypermethylation and lung cancer remains to be elucidated. Therefore, we conducted this study to evaluate the clinical significance of WIF-1 promoter hypermethylation in lung cancer. METHODS: A comprehensive literature...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptor Proteins, Signal Transducing
Share to Carcinoma, Non-Small-Cell Lung

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Methylation

Share to Gene Expression Regulation, Neoplastic

Share to Lung Neoplasms

Share to Repressor Proteins

Share to Small Cell Lung Carcinoma

Share to Wnt1 Protein

Source

Open in PubMed Open full text

Identifiers

PMID: 27930522
DOI: 10.1097/MD.0000000000005433
PMCID: PMC5265994

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Promoter hypermethylation of Wnt inhibitory factor-1 in patients with lung cancer: A systematic meta-analysis.PMID 27930522Read ↗

Wif1 hypermethylation as unfavorable prognosis of non-small cell lung cancers with EGFR mutation.Semantic proximity Read ↗

Promoter methylation of WNT inhibitory factor-1 may be associated with the pathogenesis of multiple human tumors.Semantic proximity Read ↗

Wnt inhibitory factor-1, a Wnt antagonist, is silenced by promoter hypermethylation in malignant pleural mesotheliomaSemantic proximity Read ↗

The Hypomethylation Agent Bisdemethoxycurcumin Acts on the WIF-1 Promoter, Inhibits the Canonical Wnt Pathway and Induces Apoptosis in Human Non-Small-Cell Lung CancerSemantic proximity Read ↗

DNA methylation and nonsmall cell lung cancer.Semantic proximity Read ↗

Wnt signaling as potential therapeutic target in lung cancerSemantic proximity Read ↗

Association of Wnt-Inducible Signaling Pathway Protein 1 Genetic Polymorphisms With Lung Cancer Susceptibility and Platinum-Based Chemotherapy Response.Semantic proximity Read ↗

Clinical implications of epigenetic alterations in human thoracic malignancies: epigenetic alterations in lung cancer.Semantic proximity Read ↗

Epigenetic effects of lung cancer predisposing factors impact on clinical diagnosis and prognosisSemantic proximity Read ↗

Aberrant promoter methylation of WIF-1 and SFRP1, 2, 4 genes in mesotheliomaSemantic proximity Read ↗

Synchronous alterations of Wnt and epidermal growth factor receptor signaling pathways through aberrant methylation and mutation in non small cell lung cancer.Semantic proximity Read ↗

DNA Methylation status of Wnt antagonist SFRP5 can predict the response to the EGFR-tyrosine kinase inhibitor therapy in non-small cell lung cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.