Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Sorting nexin 9 recruits clathrin heavy chain to the mitotic spindle for chromosome alignment and segregation.

PloS one - 1 Jan 2013

Ma Maggie P C, Robinson Phillip J, Chircop Megan

Abstract excerpt

Sorting nexin 9 (SNX9) and clathrin heavy chain (CHC) each have roles in mitosis during metaphase. Since the two proteins directly interact for their other cellular function in endocytosis we investigated whether they also interact for metaphase and operate on the same pathway. We report that SNX9 and CHC functionally interact during metaphase in a specific molecular pathway that contributes to stabilization of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosome Segregation
Share to Endocytosis
Share to Gene Order

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Metaphase

Share to Microtubules

Share to Protein Interaction Domains and Motifs

Share to Sorting Nexins

Share to Spindle Apparatus

Source

Open in PubMed Open full text

Identifiers

PMID: 23861900
DOI: 10.1371/journal.pone.0068387
PMCID: PMC3702553

Genes

SNX9
TACC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Sorting nexin 9 recruits clathrin heavy chain to the mitotic spindle for chromosome alignment and segregation.PMID 23861900Read ↗

Clathrin heavy chain mediates TACC3 targeting to mitotic spindles to ensure spindle stability.Semantic proximity Read ↗

Trimerisation is important for the function of clathrin at the mitotic spindleSemantic proximity Read ↗

Clathrin-mediated endocytic proteins are involved in regulating mitotic progression and completion.Semantic proximity Read ↗

Crm1 is a mitotic effector of Ran-GTP in somatic cells.Semantic proximity Read ↗

Oocyte Spindle Proteomics Analysis Leading to Rescue of Chromosome Congression Defects in Cloned EmbryosSemantic proximity Read ↗

Kinesin-14 family proteins HSET/XCTK2 control spindle length by cross-linking and sliding microtubules.Semantic proximity Read ↗

Cell transformation disrupts the efficiency of chromosome segregation through microtubule detyrosinationSemantic proximity Read ↗

Targeting of RCC1 to chromosomes is required for proper mitotic spindle assembly in human cells.Semantic proximity Read ↗

Clathrin is spindle-associated but not essential for mitosis.Semantic proximity Read ↗

Regulating chromosomal movement by the cochaperone FKB-6 ensures timely pairing and synapsis.Semantic proximity Read ↗

Kinetochore dynein generates a poleward pulling force to facilitate congression and full chromosome alignment.Semantic proximity Read ↗

Rapid degradation and 3D CLEM of condensin reveal chromatin compaction uncoupled from chromosome architecture in mitosisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.