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Article

Clathrin-mediated endocytic proteins are involved in regulating mitotic progression and completion.

Traffic (Copenhagen, Denmark) - 1 Dec 2012

Smith Charlotte M, Chircop Megan

Abstract excerpt

A few proteins required for clathrin-mediated endocytosis (CME) are associated with successful completion of mitosis at distinct mitotic stages. Clathrin heavy chain (CHC) and epsin are required for chromosome segregation independent of their CME function and dynamin II (dynII) functions in the abscission stage of cytokinesis. In this study we screened for mitotic roles of eight CME proteins: CHC, α-adaptin,...

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Identifiers

PMID: 22901037
DOI: 10.1111/tra.12001

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