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Article

Kinesin-14 family proteins HSET/XCTK2 control spindle length by cross-linking and sliding microtubules.

Molecular biology of the cell - 1 Mar 2009

Cai Shang, Weaver Lesley N, Ems-McClung Stephanie C, Walczak Claire E

Abstract excerpt

Kinesin-14 family proteins are minus-end directed motors that cross-link microtubules and play key roles during spindle assembly. We showed previously that the Xenopus Kinesin-14 XCTK2 is regulated by Ran via the association of a bipartite NLS in the tail of XCTK2 with importin alpha/beta, which regulates its ability to cross-link microtubules during spindle formation. Here we show that mutation of the nuclear...

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Identifiers

PMID: 19116309
DOI: 10.1091/mbc.e08-09-0971
PMCID: PMC2649268

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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