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Article

Cognitive manic symptoms in bipolar disorder associated with polymorphisms in the DAOA and COMT genes.

PloS one - 1 Jan 2013

Hukic Dzana Sudic, Frisén Louise, Backlund Lena, Lavebratt Catharina, Landén Mikael, Träskman-Bendz Lil, Edman Gunnar, Schalling Martin, Ösby Urban

Abstract excerpt

INTRODUCTION: Bipolar disorder is characterized by severe mood symptoms including major depressive and manic episodes. During manic episodes, many patients show cognitive dysfunction. Dopamine and glutamate are important for cognitive processing, thus the COMT and DAOA genes that modulate the expression of these neurotransmitters are of interest for studies of cognitive function. METHODOLOGY: Focusing on the most...

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Identifiers

PMID: 23861766
DOI: 10.1371/journal.pone.0067450
PMCID: PMC3702534

Genes

COMT
DAOA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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