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Article

COMT genotype increases risk for bipolar I disorder and influences neurocognitive performance.

Bipolar disorders - 1 Jun 2007

Burdick Katherine E, Funke Birgit, Goldberg Joseph F, Bates John A, Jaeger Judith, Kucherlapati Raju, Malhotra Anil K

Abstract excerpt

OBJECTIVES: Bipolar disorder (BPD) is an affective disorder characterized by episodes of depression and mania. Cognitive impairment in patients with BPD is common and recent data suggest that it may represent a trait-like feature of the illness, as it persists during periods of wellness and co-segregates in families of bipolar patients. This suggests an underlying genetic predisposition towards cognitive...

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Source

Identifiers

PMID: 17547583
DOI: 10.1111/j.1399-5618.2007.00384.x

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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