Article
Association of a nonsynonymous variant of DAOA with visuospatial ability in a bipolar family sample.
Biological psychiatry - 1 Sept 2008
Soronen Pia, Silander Kaisa, Antila Mervi, Palo Outi M, Tuulio-Henriksson Annamari, Kieseppä Tuula, Ellonen Pekka, Wedenoja Juho, Turunen Joni A, Pietiläinen Olli P H, Hennah William, Lönnqvist Jouko, Peltonen Leena, Partonen Timo, Paunio Tiina
Abstract excerpt
BACKGROUND: Bipolar disorder and schizophrenia are hypothesized to share some genetic background. METHODS: In a two-phase study, we evaluated the effect of five promising candidate genes for psychotic disorders, DAOA, COMT, DTNBP1, NRG1, and AKT1, on bipolar spectrum disorder, psychotic disorder, and related cognitive endophenotypes in a Finnish family-based sample ascertained for bipolar disorder. RESULTS: In...
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