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Article

Genome wide SNP array identified multiple mechanisms of genetic changes in Waldenstrom macroglobulinemia.

American journal of hematology - 1 Nov 2013

Poulain Stéphanie, Roumier Christophe, Galiègue-Zouitina Sylvie, Daudignon Agnès, Herbaux Charles, Aiijou Rachid, Lainelle Amélie, Broucqsault Natacha, Bertrand Elisabeth, Manier Salomon, Renneville Aline, Soenen Valérie, Tricot Sabine, Roche-Lestienne Catherine, Duthilleul Patrick, Preudhomme Claude, Quesnel Bruno, Morel Pierre, Leleu Xavier

Abstract excerpt

SNP array (SNPa) was developed to detect copy number alteration (CNA) and loss of heterozygosity (LOH) without copy number changes, CN-LOH. We aimed to identify novel genomic aberrations using SNPa in 31 WM with paired samples. Methylation status and mutation were analyzed on target genes. A total of 61 genetic aberrations were observed, 58 CNA (33 gains, 25 losses) in 58% of patients and CN-LOH in 6% of...

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Identifiers

PMID: 23861223
DOI: 10.1002/ajh.23545

Genes

DLEU7
BCR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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