Article
High-throughput genomic analysis in Waldenström's macroglobulinemia.
Clinical lymphoma, myeloma & leukemia - 1 Feb 2011
Poulain Stéphanie, Braggio Esteban, Roumier Christophe, Aijjou Rachid, Broucqsault Natacha, Galiègue-Zouitina Sylvie, Manier Salomon, Soenen Valérie, Nibourel Olivier, Duthilleul Patrick, Fonseca Rafael, Leleu Xavier
Abstract excerpt
Single-nucleotide polymorphism array (SNPa) and array-based comparative genomic hybridization (aCGH) are among the most sensitive genomic high-throughput screening techniques used in the exploration of genetic abnormalities in Waldenström's macroglobulinemia (WM). SNP and aCGH allow the identification of copy number abnormalities (CNA) at the kilobase level thus identifying cryptic genetic abnormalities unseen by...
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