Article
Polymorphisms in STK17A gene are associated with systemic lupus erythematosus and its clinical manifestations.
Gene - 25 Sept 2013
da Silva Fonseca Andréia Maria, de Azevedo Silva Jaqueline, Pancotto João Alexandre Trés, Donadi Eduardo Antônio, Segat Ludovica, Crovella Sergio, Sandrin-Garcia Paula
Abstract excerpt
Systemic lupus erythematosus (SLE) is an autoimmune disorder with several clinical manifestations. SLE etiology has a strong genetic component, which plays a key role in disease's predisposition, as well as participation of environmental factors, such and UV light exposure. In this regard, we investigated whether polymorphisms in STK17A, a DNA repair related gene, encoding for serine/threonine-protein kinase 17A,...
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