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Article

The role of environmental exposures and gene–environment interactions in the etiology of systemic lupus erythematous

10 Feb 2022

Abstract excerpt

Systemic lupus erythematosus (SLE) is a complex, chronic autoimmune disease, whose etiology includes both genetic and environmental factors. Individual genetic risk factors likely only account for about one-third of observed heritability among individuals with a family history of SLE. A large portion of the remaining risk may be attributable to environmental exposures and gene-environment interactions. This...

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PMID: 35143075
DOI: 10.1111/joim.13448

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