Article
Interleukin 17A rs2275913 polymorphism is associated with susceptibility to systemic lupus erythematosus: A meta and trial sequential analysis.
Lupus - 1 May 2022
Padhi Sunali, Sarangi Surjyapratap, Nayak Nisha, Barik Debashis, Pati Abhijit, Panda Aditya K
Abstract excerpt
BACKGROUND: The role of cytokines in the development of systemic lupus erythematosus (SLE) has received much attention. Interleukin-17 A upregulates several inflammation-related genes and is thought to have a crucial role in SLE development. The susceptibility to SLE development has been linked to functional genetic variations of the IL-17A gene; nevertheless, the findings have been conflicting. We conducted a...
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