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Article

Identification of PEAR1 SNPs and their influences on the variation in prasugrel pharmacodynamics.

Pharmacogenomics - 1 Jul 2013

Xiang Qian, Cui Yimin, Zhao Xia, Zhao Nan

Abstract excerpt

AIM: The present study aimed to investigate PEAR1 genetic polymorphisms and pharmacogenetic variability in the pharmacodynamics of prasugrel, a new oral antiplatelet agent, in healthy Han Chinese subjects. PATIENTS & METHODS: The inhibition of adenosine diphosphate-induced platelet aggregation was measured pre- and post-administration using the VerifyNow(®) P2Y12 assay. The genetic sequence of PEAR1 exons and...

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Source

Identifiers

PMID: 23859572
DOI: 10.2217/pgs.13.108

Genes

PEAR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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