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Article

Effect of PEAR1, PTGS1 gene polymorphisms on the recurrence of aspirin-treated patients with ischemic stroke in the Han population of China: A 4-year follow-up study.

Medicine - 10 May 2024

Zhang Linlin, Meng Zhongru, Wang Hongxia, Miao Yang

Abstract excerpt

Platelet endothelial aggregation receptor 1 (PEAR1) and prostaglandin endoperoxide synthase 1 (PTGS1) polymorphisms can affect laboratory aspirin resistance. However, the impact of genetic polymorphisms on the recurrence of ischemic stroke (IS) patients treated with aspirin is not fully understood. This study aimed to examine the relationship between gene polymorphisms of PEAR1 and PTGS1 and IS recurrence in...

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Identifiers

PMID: 38728491
DOI: 10.1097/MD.0000000000038031
PMCID: PMC11081601

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