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Article

A case-based reasoning system for genotypic prediction of HIV-1 co-receptor tropism.

Journal of bioinformatics and computational biology - 1 Aug 2013

Evans Mark C, Paquet Agnes C, Huang Wei, Napolitano Laura, Frantzell Arne, Toma Jonathan, Stawiski Eric W, Goetz Matthew Bidwell, Petropoulos Christos J, Whitcomb Jeannette, Coakley Eoin, Haddad Mojgan

Abstract excerpt

Accurate co-receptor tropism (CRT) determination is critical for making treatment decisions in HIV management. We created a genotypic tropism prediction tool by utilizing the case-based reasoning (CBR) technique that attempts to solve new problems through applying the solution from similar past problems. V3 loop sequences from 732 clinical samples with diverse characteristics were used to build a case library....

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PMID: 23859270
DOI: 10.1142/S0219720013500066

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CXCR4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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