Article
The development of an expert system to predict virological response to HIV therapy as part of an online treatment support tool.
AIDS (London, England) - 24 Sept 2011
Revell Andrew D, Wang Dechao, Boyd Mark A, Emery Sean, Pozniak Anton L, De Wolf Frank, Harrigan Richard, Montaner Julio S G, Lane Clifford, Larder Brendan A
Abstract excerpt
OBJECTIVE: The optimum selection and sequencing of combination antiretroviral therapy to maintain viral suppression can be challenging. The HIV Resistance Response Database Initiative has pioneered the development of computational models that predict the virological response to drug combinations. Here we describe the development and testing of random forest models to power an online treatment selection tool....
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