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Article

Jmjd3 Plays Pivotal Roles in the Proper Development of Early-Born Retinal Lineages: Amacrine, Horizontal, and Retinal Ganglion Cells.

Investigative ophthalmology & visual science - 1 Sept 2020

Iwagawa Toshiro, Honda Hiroaki, Watanabe Sumiko

Abstract excerpt

Purpose: Trimethylation of histone H3 at lysine 27 (H3K27me3) is a critical mediator of transcriptional gene repression, and Jmjd3 and Utx are the demethylases specific to H3K27me3. Using an in vitro retinal explant culture system, we previously revealed the role of Jmjd3 in the development of rod bipolar cells; however, the roles of Jmjd3 in the development of early-born retinal cells are unknown due to...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Jumonji Domain-Containing Histone Demethylases

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Identifiers

PMID: 32986815
DOI: 10.1167/iovs.61.11.43
PMCID: PMC7533738

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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