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Article

The influence of P2Y12 gene polymorphisms on clopidogrel therapy in patients after percutaneous coronary intervention.

Future cardiology - 1 Jan 2024

Pawlak Kornel, Danielak Dorota, Burchardt Paweł, Kruszyna Łukasz, Karaźniewicz-Łada Marta

Abstract excerpt

Aim: We aimed to define the influence of P2Y12 polymorphisms (rs6801273, rs2046934, and rs6809699), diabetes, hypertension, obesity, hypercholesterolemia, statins intake, and smoking habit on clopidogrel therapy in patients undergoing percutaneous coronary intervention.Materials & methods: We used PCR-RFLP and PCR-ASO for P2Y12 genotype analysis. The effectiveness of the therapy was measured with the VerifyNow...

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Share to Platelet Aggregation Inhibitors
Share to Polymorphism, Genetic
Share to Receptors, Purinergic P2Y12

Source

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Identifiers

PMID: 38953340
DOI: 10.1080/14796678.2024.2363712
PMCID: PMC11457605

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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