Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of P2Y12 single-nucleotide polymorphisms and their influences on the variation in ADP-induced platelet aggregation.

Thrombosis research - 1 Mar 2011

Lee Su-Jun, Jung Il-Sun, Jung Eun-Ji, Choi Ji-Yeop, Yeo Chang-Woo, Cho Doo-Yeoun, Kim Yang-Weon, Lee Sang-Seop, Shin Jae-Gook

Abstract excerpt

INTRODUCTION: Although P2Y12 has a significant role in normal hemostasis and thrombosis, no genetic study has been described about the association between P2Y12 variants and the extent of ADP-induced platelet activation in the Korean population. MATERIALS AND METHODS: The expression levels of two...

Topics

Adenosine Diphosphate
Adult
Haplotypes
Humans
Korea
Linkage Disequilibrium
Male
Platelet Aggregation
Polymorphism, Single Nucleotide
Receptors, Purinergic P2Y12
Young Adult

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21216445
DOI: 10.1016/j.thromres.2010.11.023

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-21216445-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of P2Y12 single-nucleotide polymorphisms and their influences on the variation in ADP-induced platelet aggregation.PMID 21216445Read ↗

Effect of P2Y1 and P2Y12 genetic polymorphisms on the ADP-induced platelet aggregation in a Korean population.Semantic proximity Read ↗

Adenosine diphosphate-induced platelet aggregation is associated with P2Y12 gene sequence variations in healthy subjects.Semantic proximity Read ↗

Study of the Association of PEAR1, P2Y12, and UGT2A1 Polymorphisms with Platelet Reactivity in Response to Dual Antiplatelet Therapy in Chinese Patients.Semantic proximity Read ↗

Gene sequence variations of the platelet P2Y12 receptor are associated with coronary artery disease.Semantic proximity Read ↗

Dimorphism in the P2Y1 ADP receptor gene is associated with increased platelet activation response to ADP.Semantic proximity Read ↗

Ticagrelor yields consistent dose-dependent inhibition of ADP-induced platelet aggregation in patients with atherosclerotic disease regardless of genotypic variations in P2RY12, P2RY1, and ITGB3.Semantic proximity Read ↗

P2Y12 H2 haplotype is associated with peripheral arterial disease: a case-control study.Semantic proximity Read ↗

P2Y12 polymorphisms and antiplatelet effects of aspirin in patients with coronary artery disease.Semantic proximity Read ↗

Associations of P2Y12R gene polymorphisms with susceptibility to coronary heart disease and clinical efficacy of antiplatelet treatment with clopidogrel.Semantic proximity Read ↗

[Genetic variants of platelet ADP receptor P2Y12 associated with changed platelet functional activity and development of cardiovascular diseases].Semantic proximity Read ↗

Common variation in the platelet receptor P2RY12 gene is associated with residual on-clopidogrel platelet reactivity in patients undergoing elective percutaneous coronary interventions.Semantic proximity Read ↗

P2RY1 and P2RY12 polymorphisms and on-aspirin platelet reactivity in patients with coronary artery disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.