Article
Identification of P2Y12 single-nucleotide polymorphisms and their influences on the variation in ADP-induced platelet aggregation.
Thrombosis research - 1 Mar 2011
Lee Su-Jun, Jung Il-Sun, Jung Eun-Ji, Choi Ji-Yeop, Yeo Chang-Woo, Cho Doo-Yeoun, Kim Yang-Weon, Lee Sang-Seop, Shin Jae-Gook
Abstract excerpt
INTRODUCTION: Although P2Y12 has a significant role in normal hemostasis and thrombosis, no genetic study has been described about the association between P2Y12 variants and the extent of ADP-induced platelet activation in the Korean population. MATERIALS AND METHODS: The expression levels of two reference sequences of P2Y12 mRNA transcripts (variants 1 and 2) were examined in the whole blood before direct DNA...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
