Article
A genomic random interval model for statistical analysis of genomic lesion data.
Bioinformatics (Oxford, England) - 1 Sept 2013
Pounds Stan, Cheng Cheng, Li Shaoyu, Liu Zhifa, Zhang Jinghui, Mullighan Charles
Abstract excerpt
MOTIVATION: Tumors exhibit numerous genomic lesions such as copy number variations, structural variations and sequence variations. It is difficult to determine whether a specific constellation of lesions observed across a cohort of multiple tumors provides statistically significant evidence that the lesions target a set of genes that may be located across different chromosomes but yet are all involved in a single...
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