Article
GEAR: genomic enrichment analysis of regional DNA copy number changes.
Bioinformatics (Oxford, England) - 1 Feb 2008
Kim Tae-Min, Jung Yu-Chae, Rhyu Mun-Gan, Jung Myeong Ho, Chung Yeun-Jun
Abstract excerpt
UNLABELLED: We developed an algorithm named GEAR (genomic enrichment analysis of regional DNA copy number changes) for functional interpretation of genome-wide DNA copy number changes identified by array-based comparative genomic hybridization. GEAR selects two types of chromosomal alterations with potential biological relevance, i.e. recurrent and phenotype-specific alterations. Then it performs functional...
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