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Article

A comparative analysis of algorithms for somatic SNV detection in cancer.

Bioinformatics (Oxford, England) - 15 Sept 2013

Roberts Nicola D, Kortschak R Daniel, Parker Wendy T, Schreiber Andreas W, Branford Susan, Scott Hamish S, Glonek Garique, Adelson David L

Abstract excerpt

MOTIVATION: With the advent of relatively affordable high-throughput technologies, DNA sequencing of cancers is now common practice in cancer research projects and will be increasingly used in clinical practice to inform diagnosis and treatment. Somatic (cancer-only) single nucleotide variants (SNVs) are the simplest class of mutation, yet their identification in DNA sequencing data is confounded by germline...

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PMID: 23842810
DOI: 10.1093/bioinformatics/btt375
PMCID: PMC3753564

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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