Article
Evolution of type 2 vaccine derived poliovirus lineages. Evidence for codon-specific positive selection at three distinct locations on capsid wall.
PloS one - 1 Jan 2013
Hovi Tapani, Savolainen-Kopra Carita, Smura Teemu, Blomqvist Soile, Al-Hello Haider, Roivainen Merja
Abstract excerpt
Partial sequences of 110 type 2 poliovirus strains isolated from sewage in Slovakia in 2003-2005, and most probably originating from a single dose of oral poliovirus vaccine, were subjected to a detailed genetic analysis. Evolutionary patterns of these vaccine derived poliovirus strains (SVK-aVDPV2) were compared to those of type 1 and type 3 wild poliovirus (WPV) lineages considered to have a single seed strain...
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