Characteristics of an environmentally monitored prolonged type 2 vaccine derived poliovirus shedding episode that stopped without intervention.

doi:10.1371/journal.pone.0066849

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Article

Characteristics of an environmentally monitored prolonged type 2 vaccine derived poliovirus shedding episode that stopped without intervention.

PloS one - 1 Jan 2013

Hovi Tapani, Paananen Anja, Blomqvist Soile, Savolainen-Kopra Carita, Al-Hello Haider, Smura Teemu, Shimizu Hiroyuki, Nadova Katarina, Sobotova Zdenka, Gavrilin Eugene, Roivainen Merja

Abstract excerpt

Vaccine derived poliovirus (VDPV) type 2 strains strongly divergent from the corresponding vaccine strain, Sabin 2, were repeatedly isolated from sewage in Slovakia over a period of 22 months in 2003-2005. Cell cultures of stool specimens from known immune deficient patients and from an identified putative source population of 500 people failed to identify the potential excretor(s) of the virus. The occurrence of...

Topics

Amino Acid Sequence
Amino Acid Substitution
Animals
Antibodies, Viral
Capsid Proteins
Child
Environmental Microbiology
Genetic Variation
Humans
Mice

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mice, Transgenic

Models, Molecular

Molecular Sequence Data

Phylogeny

Poliovirus

Poliovirus Vaccine, Oral

Protein Multimerization

Seasons

Source

Open in PubMed Open full text

Identifiers

PMID: 23935826
DOI: 10.1371/journal.pone.0066849
PMCID: PMC3729856

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-23935826-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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