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Article

Isolation and characterization of a type 2 vaccine-derived poliovirus from environmental surveillance in China, 2012.

PloS one - 1 Jan 2013

Tao Zexin, Zhang Yong, Liu Yao, Xu Aiqiang, Lin Xiaojuan, Yoshida Hiromu, Xiong Ping, Zhu Shuangli, Wang Suting, Yan Dongmei, Song Lizhi, Wang Haiyan, Cui Ning, Xu Wenbo

Abstract excerpt

Environmental surveillance of poliovirus on sewage has been conducted in Shandong Province, China since 2008. A type 2 vaccine-derived poliovirus (VDPV) with 7 mutations in VP1 coding region was isolated from the sewage collected in the city of Jinan in December 2012. The complete genome sequencing analysis of this isolate revealed 25 nucleotide substitutions, 7 of which resulted in amino acid alteration. No...

Topics

China
Environmental Monitoring
Evolution, Molecular
Genome, Viral
Phenotype
Phylogeny
Poliovirus
Poliovirus Vaccines
Sewage
Temperature
Vaccination

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24386319
DOI: 10.1371/journal.pone.0083975
PMCID: PMC3873410

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