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Article

Derivation and Validation of a Genotype- Guided Warfarin Dosing Model in a Mixed Arab Population.

Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis - 1 Jan 2026

Fahmi Amr M, Bardissy Ahmed El, Saad Mohamed Omar, Eljilany Islam, Bader Loulia, Elewa Hazem

Abstract excerpt

BackgroundPrevious studies demonstrated the superiority of a genotype-guided warfarin dosing (GWD) method for warfarin initiation. International GWD models such as Gage et al model were validated in diverse populations but Arab patients were not well represented in these studies.ObjectiveTo derive and validate a GWD model in an Arab population and compare the outcomes to Gage et al model.MethodsIn this...

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Identifiers

PMID: 42262158
DOI: 10.1177/10760296261439536
PMCID: PMC13250413

Genes

CYP2C9
VKORC1
CYP4F2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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