Article
Calmodulin expression distinguishes the smooth muscle cell population of human carotid plaque.
The American journal of pathology - 1 Sept 2013
Coen Matteo, Marchetti Giovanna, Palagi Patricia M, Zerbinati Carlotta, Guastella Giuseppe, Gagliano Teresa, Bernardi Francesco, Mascoli Francesco, Bochaton-Piallat Marie-Luce
Abstract excerpt
Several observations suggest the expansion of a distinct medial smooth muscle cell (SMC) subset in atherosclerosis and restenosis. We characterized the phenotypic features of SMC subsets in cultures derived from human carotid endarterectomy specimens. Specimens comprised an undiseased portion (thin intimal thickening with the underlying media) and a diseased portion (atherosclerotic plaque with the underlying...
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