Article
Pharmacogenetics of Adverse Drug Reactions.
Advances in pharmacology (San Diego, Calif.) - 1 Jan 2018
Osanlou Orod, Pirmohamed Munir, Daly Ann K
Abstract excerpt
Adverse drug reactions (ADRs) are an important cause of morbidity and mortality. Genetic factors predispose to many ADRs, affecting susceptibility to both type A and type B reactions. The overall contribution of genetics will vary according to drug and ADR, and should be considered when attempting to predict and prevent ADRs. Genetic risk factors are considered in detail for a number of type A ADRs, especially...
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