Article
The association of single nucleotide polymorphism of the Fyn gene with sporadic Alzheimer's disease in the Chinese Han population.
Neuroscience letters - 11 Jul 2014
Li Jing, Zhou Hua-Dong, Deng Juan, Zhu Jie, Li Lin, Zhang Meng, Zeng Fan, Wang Yan-Jiang
Abstract excerpt
Recent studies suggested genetic factors contribute to the pathogenesis of sporadic Alzheimer's disease (sAD). Fibroblast Yes related novel (Fyn), a tau kinase, has been reported to be associated with aberrant phosphorylated tau and neurofibrillary tangles formation. Fyn gene may be a potential candidate gene for AD. To investigate the association of the polymorphisms in Fyn gene with the susceptibility to sAD,...
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