Article
Discriminating between allele- and genotype-specific transmission ratio distortion.
Animal genetics - 1 Dec 2020
Casellas J, Id-Lahoucine S, Cánovas A
Abstract excerpt
Transmission ratio distortion (TRD) is defined as the observed deviation from the expected Mendelian inheritance of alleles from heterozygous parents. This phenomenon is attributed to various biological mechanisms acting on germ cells, embryos or fetuses, or even in early postnatal life. Current statistical approaches typically use two independent parametrizations assuming that TRD relies on allele- or...
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