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Article

Distortion of Mendelian segregation across the Angus cattle genome uncovering regions affecting reproduction.

Scientific reports - 17 Aug 2023

Id-Lahoucine S, Casellas J, Lu D, Sargolzaei M, Miller S, Cánovas A

Abstract excerpt

Nowadays, the availability of genotyped trios (sire-dam-offspring) in the livestock industry enables the implementation of the transmission ratio distortion (TRD) approach to discover deleterious alleles in the genome. Various biological mechanisms at different stages of the reproductive cycle such as gametogenesis, embryo development and postnatal viability can induce signals of TRD (i.e., deviation from...

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Identifiers

PMID: 37591956
DOI: 10.1038/s41598-023-37710-z
PMCID: PMC10435455

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