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Article

Evidence for extensive transmission distortion in the human genome.

American journal of human genetics - 1 Jan 2004

Zöllner Sebastian, Wen Xiaoquan, Hanchard Neil A, Herbert Mark A, Ober Carole, Pritchard Jonathan K

Abstract excerpt

It is a basic principle of genetics that each chromosome is transmitted from parent to offspring with a probability that is given by Mendel's laws. However, several known biological processes lead to skewed transmission probabilities among surviving offspring and, therefore, to excess genetic sharing among relatives. Examples include in utero selection against deleterious mutations, meiotic drive, and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 14681832
DOI: 10.1086/381131
PMCID: PMC1181913

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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