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Article

Genomic screening of allelic and genotypic transmission ratio distortion in horse.

PloS one - 1 Jan 2023

Laseca Nora, Cánovas Ángela, Valera Mercedes, Id-Lahoucine Samir, Perdomo-González Davinia I, Fonseca Pablo A S, Demyda-Peyrás Sebastián, Molina Antonio

Abstract excerpt

The phenomenon in which the expected Mendelian inheritance is altered is known as transmission ratio distortion (TRD). The TRD analysis relies on the study of the transmission of one of the two alleles from a heterozygous parent to the offspring. These distortions are due to biological mechanisms affecting gametogenesis, embryo development and/or postnatal viability, among others. In this study, TRD phenomenon...

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PMID: 37556504
DOI: 10.1371/journal.pone.0289066
PMCID: PMC10411798

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