Article
Genetic variants of membrane metallopeptidase genes in inflammatory bowel diseases.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver - 1 Dec 2013
Tavano Francesca, Palmieri Orazio, di Mola Fabio Francesco, Latiano Anna, Burbaci Francesca Paola, Valvano Maria Rosa, Corritore Giuseppe, Augello Bartolomeo, Merla Giuseppe, Annese Vito, Andriulli Angelo, di Sebastiano Pierluigi
Abstract excerpt
BACKGROUND: The substance P pathway modulates neuroimmune interactions during intestinal inflammation. AIMS: To analyse mucosal expression and genetic variants of the genes coding for substance P, neurokinin-1 receptor and neutral endopeptidase in patients with inflammatory bowel disease. METHODS: qRT-PCR was used to analyse mRNA levels in matched, paired samples of inflamed colonic mucosa and adjacent...
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