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Article

Crohn's Colitis: Development of a multiplex gene expression assay comparing mRNA levels of susceptibility genes.

Clinics and research in hepatology and gastroenterology - 1 Sept 2017

Russo Edda, Lombardelli Letizia, Giudici Francesco, Cavalli Tiziana, Ficari Ferdinando, Fazi Marilena, Scaringi Stefano, Biancone Livia, Logiodice Federica, Nesi Mariateresa, Latiano Anna, Annese Vito, Torcia Maria Gabriella, Bechi Paolo, Tonelli Francesco, Piccinni Marie-Pierre, Malentacchi Cecilia

Abstract excerpt

Crohn's disease (CD) is a multifactorial immunologically mediated disease. In this study we explored, for the first time, the efficacy of the Multiplex Gene Assay technology for detecting mRNA expression profile of 24 selected CD related genes in endoscopic biopsies and surgical specimens from CD patients with colonic localization of the disease. The polymorphisms of genes most frequently associated with CD were...

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Identifiers

PMID: 28365139
DOI: 10.1016/j.clinre.2017.02.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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