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Article

DNA diagnosis in a microseparator based on particle aggregation.

Biosensors & bioelectronics - 15 Dec 2013

Chen Yu-Tzu, Liu Yen-Cheng, Fang Wei-Feng, Huang Chao-Jyun, Fan Shih-Kang, Chen Wen-Jone, Chang Wei-Tien, Huang Chien-Hua, Yang Jing-Tang

Abstract excerpt

A novel aggregation-based biosensing method to achieve detection of oligonucleotides in a pinched-flow fractionation (PFF) microseparator was developed. Employing functionalized polystyrene microspheres, this method is capable of the direct detection of the concentration of a specific DNA sequence. The label-free target DNA hybridizes with probe DNA of two kinds on the surface of the microspheres and causes the...

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Identifiers

PMID: 23827371
DOI: 10.1016/j.bios.2013.06.017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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