Article
A case of adaptation through a mutation in a tandem duplication during experimental evolution in Escherichia coli.
BMC genomics - 3 Jul 2013
Maharjan Ram P, Gaffé Joël, Plucain Jessica, Schliep Martin, Wang Lei, Feng Lu, Tenaillon Olivier, Ferenci Thomas, Schneider Dominique
Abstract excerpt
BACKGROUND: DNA duplications constitute important precursors for genome variation. Here we analyzed an unequal duplication harboring a beneficial mutation that may provide alternative evolutionary outcomes. RESULTS: We characterized this evolutionary event during experimental evolution for only 100 generations of an Escherichia coli strain under glucose limitation within chemostats. By combining Insertion...
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